aldehyde dehydrogenase (aldh) — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4778	3-Hydroxybenzaldehyde		Others , Dehydrogenase
	3-Hydroxybenzaldehyde is a compound useful in organic synthesis.		Others , Dehydrogenase
TJS1382	Taraxerone		Dehydrogenase
	Taraxerone has allelopathic and antifungal effects.Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration with the concentration dep...		Dehydrogenase
T12196	NCT-505		Dehydrogenase
	NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1, IC50 = 7 nM) and a weak inhibitor of hALDH1A2, hALDH1A3, hALDH2, hALDH3A1 with IC50 values of >57 μM, 22.8 μM, 20.1 μM, >57 μM respectively...		Dehydrogenase
T6903	NCT-501	NCT501	Dehydrogenase
	NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM.		Dehydrogenase
T2662	Alda-1	Alda 1	Apoptosis , Dehydrogenase
	Alda-1 is an ALDH2 agonist, a cell-permeable activator of both the wild-type ALDH21 and the Asian E487K mutant ALDH22 forms of mitochondrial aldehyde dehydrogenase 2 (mtALDH2).		Apoptosis , Dehydrogenase
T7835	CM10	CM 10	Dehydrogenase
	CM10 is an aldehyde dehydrogenase 1A family(ALDH1A) inhibitor.		Dehydrogenase
T10140	4-Diethylaminobenzaldehyde		Dehydrogenase
	4-Diethylaminobenzaldehyde is a reversible aldehyde dehydrogenase (ALDH) inhibitor (Ki: 4 nM for ALDH1). It displays a potent anti-androgenic effect (IC50: 1.71μM).		Dehydrogenase
T4S0878	Prunetin	Prunusetin	ERK , Dehydrogenase , NF-κB
	1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesit...		ERK , Dehydrogenase , NF-κB
T23533	WIN 18446		Dehydrogenase
	inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2)		Dehydrogenase
T10148	4-Hydroxynonenal	4-HNE	Dehydrogenase , Endogenous Metabolite
	4-Hydroxynonenal (4-HNE) (4-HNE) is an oxidative/nitrosative stress biomarker. It is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2).		Dehydrogenase , Endogenous Metabolite
T0054	Disulfiram	Tetraethylthiuram disulfide,NSC 190940,TETD	Dehydrogenase , Interleukin , Pyroptosis
	Disulfiram (TETD) is an inhibitor of the acetaldehyde dehydrogenase ALDH, inhibiting hALDH1 and hALDH2 (IC50=0.15/1.45 μM) with specificity. Disulfiram is acutely sensitized to alcohol and also inhibits GSDMD pore format...		Dehydrogenase , Interleukin , Pyroptosis
T1389	Dyclonine hydrochloride	Dyclocaine hydrochloride,Dyclonine HCl	Sodium Channel , Antibacterial , Antifungal
	Dyclonine hydrochloride (Dyclonine HCl) , an over the counter throat lozenge, is found in Sucretswith local anesthetic effect .		Sodium Channel , Antibacterial , Antifungal
T15022	CVT-10216		Dehydrogenase
	CVT-10216 is a Potent and selective, reversible inhibitor of aldehyde dehydrogenase 2 (ALDH2) (IC50: 29 nM). CVT-10216 also has inhibitory effect of ALDH-1 (IC50: 1.3 μM). CVT-10216 can reduce excessive alcohol drinking...		Dehydrogenase
T69366	CM39
	CM39 is an ALDH inhibitor. Aldehyde dehydrogenase (ALDH) activity is commonly used as a marker to identify cancer stem-like cells. The three ALDH1A isoforms have all been individually implicated in cancer stem-like cells...
T37533	DOPAL
	DOPAL is an aldehyde product of the oxidative deamination of dopamine by monoamine oxidase.[1] It can be further oxidized to 3,4-dihydroxyphenylacetic acid (DOPAC) by aldehyde dehydrogenase (ALDH) and, to a lesser extent...
T60363	Nitrefazole
	Nitrefazole, a 4-nitroimidazole derivative, exhibits potent and prolonged inhibition of aldehyde dehydrogenase (ALDH), an enzyme critical for alcohol metabolism.
T37869	BODIPY aminoacetaldehyde
	BODIPY aminoacetaldehyde (BAAA) is a fluorescent substrate applicable to both murine and human aldehyde dehydrogenase (ALDH). It comprises an aminoacetaldehyde moiety chemically bonded to the BODIPY fluorochrome. BAAA ca...
T76159	Aldehyde dehydrogenase (NAD(P))
	Aldehyde dehydrogenase NAD(P) (ALDH) is an enzyme that facilitates the conversion of aldehydes into their respective carboxylic acids while simultaneously reducing the cofactor NAD(P) to NAD(P)H, making it a key componen...
T39485	NCT-501 hydrochloride
	NCT-501 hydrochloride is a highly potent and selective inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), which is based on theophylline. It effectively inhibits hALDH1A1 with an IC50 value of 40 nM, exhibiting superior ...
T35543	Methyl Diethyldithiocarbamate
	Methyl diethyldithiocarbamate is an active metabolite of the aldehyde dehydrogenase inhibitor disulfiram .1It is produced by methylation of the disulfiram metabolite diethyldithiocarbamate in mouse liver microsomes.2Meth...